Diaz-Perales A, Collada C, Blanco C, et al. USES: Horse chestnut has been used for swelling and pain due to varicose veins and poor circulation in the legs.Some herbal/dietary supplement products have been found to contain possibly harmful impurities/additives. View abstract. Much more important is the escin component (the active compound), which should be between 100–150 milligrams per day. [Evaluation of internally effective venous drugs].

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat..

Vasa 1983;12(4):377-382.

2002;21(4):305-315. (horse chestnut).Common Name(s): Aesculaforce, Buckeye, California buckeye, Castanea equine, Chestnut, Essaven, Horse chestnut, Japanese horse chestnut, Ohio buckeye, Semen hippocastani. Unfortunately, many of the horse chestnut trees in Britain are in danger of extinction from a combination of leaf-miner moth infestation and disease. Horse chestnut is a promising alternative, and clinical studies have demonstrated that supplementing with horse chestnut seed extract may help relieve the pain and swelling of varicosities.

(8). 2002;3(5):341-348. VERY HIGH means that most of the scientific research agrees.

Examine.com is intended to be used for educational and information purposes only. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. Because of the glycosides and saponins found in horse chestnuts, they aren’t fit for humans to eat. Spider veins are a group of widened veins that can be seen through the surface of the skin. Fang, Y., Zhao, L., Yan, F., Xia, X., Xu, D., and Cui, X. Escin improves sperm quality in male patients with varicocele-associated infertility.

The anti-inflammatory properties of horse chestnut seed extract may help relieve symptoms of hemorrhoids by reducing inflammation and swelling in the affected veins (17). Rudofsky G and et al.

Generic Drugs, Are They as Good as Brand-Names? MedicineNet does not provide medical advice, diagnosis or treatment. Horse chestnut might increase the risk of bleeding if used before surgery. Gastric lavage and symptomatic treatment have been suggested.Duke 1985, Hardin1974, A 30% ethanol extract of the seed was not mutagenic in the Salmonella test, and a 40% extract was not teratogenic or embryotoxic in rats or rabbits. View abstract. Medical edema protection-clinical benefit in patients with chronic deep vein incompetence. View abstract.

The most drastic of these were Jurkat cells, used to test a type of cancer known as acute T-cell leukemia, in which the lab tests found a cell death rate of nearly 94 percent. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs.

This condition is characterized by non-functioning valves in.

An Apple a Day Keeps the Doctor Away — Fact or Fiction?

SIDE EFFECTS: Upset stomach, headache, and dizziness may occur. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. All factual claims are

NOTES: Keep all regular medical and laboratory appointments. View abstract. Specific assays have been described to quantify the aescin content of preparations, including high-pressure liquid chromatography, thin-layer chromatography, and mass spectroscopy.Curir 2007, Kapusta 2007, Ogawa 2008, Sirtori 2001, WHO 2004, Inhibition of cyclooxygenase activity of Japanese horse chestnut seed extract has been demonstrated in animal experiments.Guillaume 1994, Sato 2006, Sato 2007 The bark of Aesculus is also reported to possess the anti-inflammatory steroids stigmasterol, alpha-spinasterol, and beta-sitosterol.Senatore 1989, Tsutsumi 1967.

(1), Other contemporary but untested uses of horse chestnut include enlarged prostate, menstrual pain and eczema. Cochrane.Database.Syst.Rev.

(, Although the origin of the name “horse chestnut” is usually based on their use with horses, another potential contributing factor is the fact that the leaf stalk leaves a “scar” on the tree after falling that resembles an inverted horseshoe with nail holes. Conker trees, as they’re also known, are particularly popular in Great Britain.

(11), This particular form of infertility is caused by enlarged varicose veins within the scrotum and affects 15 out of 100 men overall and 40 out of 100 men with diagnosed or known infertility.

More human studies in this area are needed before firm conclusions can be made.

Rare cases of allergy and anaphylaxis have been reported.

These studies show that horse chestnut extract may be effective for treating CVI short term, but more research is needed to determine its long-term effects. Supplements of horse chestnut contain an ingredient called escin — not to be confused with the poisonous esculin found in raw horse chestnuts.

Taking horse chestnut along with diabetes medications might cause your blood sugar to go too low. Pittler, M. H. and Ernst, E. Horse chestnut seed extract for chronic venous insufficiency. 8-24-1968;33:1781-1785.

Lange, S., Freitag, G., and Trampisch, H. J. The main active constituents isolated from horse chestnut are aescin (10%) and prosapogenin. View abstract.

Use only standardized horse chestnut seed extract products that have had the toxin removed.



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